Gene expression is controlled, in part, by the interactions between genes and regulatory elements located along the genome. Those interactions depend on the ability of chromatin—a mix of DNA and proteins—to move around within a crowded space.…
Penn Engineers have developed a new way to use AI to solve inverse partial differential equations (PDEs), a particularly challenging class of mathematical problems with broad implications for understanding the natural world.
Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic fingerprint.” Some of the enzymes gather around damaged…
