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Eosinophils drive intestinal remodelling and innate defence in reproduction
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Eosinophils drive intestinal remodelling and innate defence in reproduction

Nature·Lim, Ai Ing·6 months ago
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Mammalian reproduction requires substantial immune adaptations to safeguard reproductive success and to ultimately shape the evolutionary trajectories of a species.…

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Postprandial lipid metabolism durably enhances T cell immunity
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Postprandial lipid metabolism durably enhances T cell immunity

Nature·Delgoffe, Greg M.·6 months ago
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Although intrinsic metabolic pathways have critical roles in T cell function1,2, systemic nutrient availability is in constant flux. Yet, how postprandial metabolism affects T cell fate has been less studied.…

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Netrin1 blockade alleviates resistance to chemotherapy in pancreatic cancer
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Netrin1 blockade alleviates resistance to chemotherapy in pancreatic cancer

Nature·Mehlen, Patrick·6 months ago
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Netrin1, a developmental cue, is a master regulator of tumour epithelial-to-mesenchymal transition (EMT)1, a mechanism that is known to drive resistance to chemotherapy2.…

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