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mold: A Massively Parallel Linker
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mold: A Massively Parallel Linker

Hacker News·about 1 month ago
#jxGVgApS

Linking is a critical step in the software build process that combines compiled object files into a single executable or shared library. Despite decades of engineering effort, link times remain a significant bottleneck in the edit-compile-debug cycle,…

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Non-chemist here is a Val-Cit + trimethyl lock linker a plausible fix for lysosomal ion trapping of basic-amine payloads?

Reddit r/Biochemistry·u/2154life·5 months ago
#mZfxCeOC

I work in IT, not chemistry. I've been reading papers on antibody-drug conjugates and peptide-drug conjugates for a while because I find the problem interesting, and I ended up sketching out an idea that I can't tell is obvious, already-done, or nonsense.…

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Non-chemist here is a Val-Cit + trimethyl lock linker a plausible fix for lysosomal ion trapping of basic-amine payloads?

Reddit r/molecularbiology·u/2154life·5 months ago
#bEhX0tGa

I work in IT, not chemistry. I've been reading papers on antibody-drug conjugates and peptide-drug conjugates for a while because I find the problem interesting, and I ended up sketching out an idea that I can't tell is obvious, already-done, or nonsense.…

15s
Read More