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Monolithically and in situ integrated PbS infrared imagers
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Monolithically and in situ integrated PbS infrared imagers

Nature·Sen Li·about 11 hours ago
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Image sensors are critical components in artificial intelligence1–3, yet conventional approaches bond detector arrays to readout integrated circuits (ROICs), a process that increases complexity and cost4.…

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Molecular underpinnings of rheumatic diseases and emerging therapeutic concepts
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Molecular underpinnings of rheumatic diseases and emerging therapeutic concepts

Nature·Gerhard Krönke·about 11 hours ago
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Inflammatory rheumatic diseases such as rheumatoid arthritis, psoriatic arthritis and systemic lupus erythematosus represent chronic inflammatory disorders that are caused by dysregulation of innate and adaptive immune responses.…

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Narrow carbon pentaheptite nanoribbon as a covalent metal
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Narrow carbon pentaheptite nanoribbon as a covalent metal

Nature·Jianmin Huang·about 11 hours ago
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Metallic carbon-based nanoribbons are sought after1,2 as atomically defined one-dimensional conductors with potential relevance to future carbon-based electrodes and interconnects3, ideally with quantum-limited conductance comparable to metallic carbon…

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Connectome simulations identify a central pattern generator for fly walking
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Connectome simulations identify a central pattern generator for fly walking

Nature·Sarah M. Pugliese·about 11 hours ago
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Animal locomotion relies on rhythmic body movements driven by central pattern generators (CPGs): neural circuits that produce oscillating output without oscillating input. However, the circuit structure of a CPG for walking is not known in any animal1,2.…

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Tandem repeat variation shapes immune cell type-specific gene expression
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Tandem repeat variation shapes immune cell type-specific gene expression

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Tandem repeats (TRs)—highly polymorphic, repetitive sequences across the human genome—are important regulators of gene expression but remain underexplored due to challenges in accurate genotyping and analysis1.…

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An unexpected function of a cell-cycle enzyme might explain the toxic effects of its inhibitors
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An unexpected function of a cell-cycle enzyme might explain the toxic effects of its inhibitors

Nature·about 11 hours ago
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A previously unknown mechanism required for cells to start proliferating has been identified. A combination of mathematical modelling and cell-based experiments shows that the enzyme WEE1 switches off a protein-degradation complex to allow cell…

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Clues about complex life come from freshly cultivated archaea
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Clues about complex life come from freshly cultivated archaea

Nature·about 11 hours ago
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Two archaeal strains that belong to a lineage closely related to the ancestor of eukaryotic cells (complex cells with membrane-bound organelles) have been brought into culture.…

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Lactate takes a shortcut into mitochondria to power the heart
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Lactate takes a shortcut into mitochondria to power the heart

Nature·Trace Thome·about 11 hours ago
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A cellular fuel called lactate is channelled directly into energy-generating organelles in heart muscle, defying the prevailing view about lactate transport.

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Tethered to stone: how rock and water availability shaped early desert occupation
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Tethered to stone: how rock and water availability shaped early desert occupation

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Fresh water in deserts often points to sites with signs of early humans and stone tools. But, in Arabia’s Rub’ al Khali region, water alone does not predict occupation.

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