You’ve probably heard the anti-meth ad campaign slogan before: “Meth: Not Even Once.” The idea is that doing meth just one time can potentially ruin your life, which, given what little I know about meth, it does not seem like a casual thing you do to blow off some steam from time to time. It’s a lifetime commitment, for as short as that lifetime may be because of it. While that may ring true for methamphetamine, newer research suggests a very different story when it comes to psychedelics like psilocybin, the active compound in magic mushrooms .

A study published in Nature Communications found that a single controlled dose of psilocybin may actually lead to measurable, and potentially positive, changes in the brain.…