The Israeli prime minister has pledged to overthrow Tehran’s government and made striking first a central principle of his security doctrine

Israel is prepared to attack Iran without US participation if necessary, Prime Minister Benjamin Netanyahu has said, pledging to overthrow Tehran’s government and make striking first a central principle of his security doctrine.

The declaration comes amid ongoing indirect negotiations over the war launched by the US and Israel in February. Israel, a major recipient of American military funding and weapons, has justified its offensives on security grounds, even as the conflict has spread across the region, disrupted Hormuz shipping, and driven up global energy prices.

Presenting his security doctrine in a speech on Sunday, Netanyahu argued that Iran would rebuild its nuclear and military capabilities as long as its government survived and made clear that Israel was prepared to launch further attacks without waiting for American participation.

“If we need to act…