The San Francisco 49ers are sitting at 6-1 at the bye week , so there is not too much to get discouraged over. However, the team has had some disappointing developments. What are the biggest disappointments through the first seven weeks of the 2026 season?

Injury Issues Once Again

Another year, more injury problems. The team cannot escape it. They signed Mike Evans despite injury concerns, and those have popped up. The same can be said with Deebo Samuel. Injuries are starting to become a known story for Nick Bosa as well.

Still, some have been more random. Rookie De’Zhaun Stribling has not been healthy. Marques Sigle and Upton Stout have missed time in the secondary. Both Alfred Collins and C.J. West got injured up front. The bye week is expected to help get the team healthy. At the same time, the expectation is for a new name to pop up in a week or two.

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Secondary Depth

The 49ers went out of their way to improve the secondary depth this offseason.…