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Major U.S. and international airline groups are pushing back against a new Ebola-related travel requirement that will affect millions of people flying into the United States.

Beginning Nov. 3, all passengers on international flights to the U.S. will have to confirm that they have not been in the Democratic Republic of the Congo (DRC) during the previous 21 days, according to the Centers for Disease Control and Prevention (CDC).

The requirement applies to everyone flying into or connecting through the U.S. — including American citizens, green card holders and airline crew members, the CDC said.

US ISSUES URGENT TRAVEL WARNING AS DEADLY EBOLA OUTBREAK SPREADS OVERSEAS

Travelers will have to complete a paper or digital statement before boarding, even if they have never visited the DRC.

Airlines must collect the forms and keep them for at least 42 days after the flight arrives in the U.S., according to the CDC.

Beginning Nov.…