David Benavidez, left, faces off with WBA/WBO cruiserweight champion Gilberto Ramirez. Steven Marcus/ The Sun via AP

The WBA and WBO unified cruiserweight titles are on the line as David Benavidez and Gilbert “Zurdo” Ramirez are set to clash Saturday evening at T-Mobile Arena in Las Vegas.

Benavidez makes the jump from light heavyweight by 25 pounds, with hopes of becoming a three-division champion and amplifying his bid for a future shot against Canelo Alvarez.

But before he gets there, Ramirez, a two-division world champion himself, stands in the way of “The Mexican Monster.”

Benavidez is the clear favorite in the eyes of oddsmakers, listed at -550 on DraftKings Sportsbook , while Ramirez is a significant underdog at +400.

The preliminary part of the card begins at 5:30 p.m. ET on YouTube, with the main card moving to Amazon Prime Video and DAZN at 8 p.m. ET.

Benavidez and Ramirez are expected to make their ring walks around 11:20 p.m.…