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Stealth switch in tuberculosis enzyme could open route to drug-resistant treatment
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Stealth switch in tuberculosis enzyme could open route to drug-resistant treatment

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Communications Biology (2026). DOI: 10.1038/s42003-026-09821-6, Creative Commons 4.0 license ."> Structure of Mtb ICL2, which forms a homotetramer. Each monomer is indicated by a different colour with one monomer coloured according to the three features present in each monomer. The active site and acetyl-CoA-binding site are also labelled. Credit: Communications Biology (2026). DOI: 10.1038/s42003-026-09821-6, Creative Commons 4.0 license .

Recent research published in Communications Biology marks an advance in structural biology by enhancing understanding of protein regulation mechanisms in Mycobacterium tuberculosis (Mtb), a global health threat.…

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