Just before the Artemis II crew began its historic slingshot around the moon this past April, NASA announced plans to build Space Reactor-1 Freedom. SR-1, the first-ever nuclear-reactor-­powered interplanetary spacecraft, is meant to fly an uncrewed mission to Mars by the end of 2028, arriving in 2029. A successful mission would herald a new era of more efficient, potentially faster spaceflight—saving astronauts time and cutting their exposure to harmful cosmic radiation as they travel to Mars and beyond. “You wake up to that announcement, and it puts a big smile on your face,” says Simon Middleburgh, co-director of the Nuclear Futures Institute at Bangor University in Wales.

The sticking points

Running a nuclear reactor in space may sound like lunacy, but it’s not. The Soviet Union sent dozens of reactors into orbit, often to power spy satellites. And experts say there aren’t any major technical obstacles to making nuclear space propulsion happen.…