Few sneaker collaborations carry the same meaning as Nike’s Doernbecher Freestyle program. What began in 2004 as a partnership between Nike and OHSU Doernbecher Children’s Hospital has grown into one of the most anticipated annual collections, giving young patients the opportunity to tell their stories through footwear. Now in its 22nd year, the program returns with six new designs that put creativity, individuality, and purpose at the forefront.

Over the years, Doernbecher Freestyle has raised more than $44 million for the hospital, with each collection offering something far more personal than a new colorway. Working alongside Nike’s design teams, six young patients spend months bringing their ideas to life, drawing inspiration from everything that makes them who they are.…