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College football prediction, pick: Midweek MACtion features Buffalo, Miami (Ohio)

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November 2, 2026 - 10:07 am

MACtion is back as the Mid-American Conference takes center stage Tuesday night with two games on the schedule.

The conference that helped popularize weekday college football will replace Conference USA this week and keep alive a stretch of 61 consecutive days of football.

Ohio vs. Akron and Buffalo vs. Miami (Ohio) headline the night, with ideal fall weather expected across the Buckeye State. Weather will not be a factor, allowing bettors to focus solely on the matchups.

Buffalo at Miami (Ohio) (-6, 44)

5 p.m. Tuesday, ESPN

Both teams enter this game at 3-1 in conference play, making it a significant game in the race for a spot in the Mid-American Conference Championship Game on the first Friday of December in Detroit.

Conference records require some context in the MAC. Some teams are among the weakest in the league, while others have proven much tougher.…

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