ROME (AP) — Pope Leo XIV is kicking off a three-nation tour of Latin America with a visit to Uruguay, the region’s least Catholic and most secular country, three weeks after undergoing lung cancer surgery that had put the entire trip into question.

Leo is due to arrive in Montevideo after a 13-and-a-half hour flight from Rome. He has a packed three-day itinerary in Uruguay including a visit to a neighborhood plagued by gang violence, a Mass in Paysandú, some 375 kilometers (230 miles) from the capital, and another Mass in the city of Florida, about 100 kilometers (60 miles) away.

The Uruguay leg is the first stop on what will be the longest and farthest trip of his pontificate, all being undertaken as the 71-year-old pope continues his recovery. The trip will also bring him to neighboring Argentina and finally back home to Peru, where Leo served as a missionary priest and bishop for two decades.

“His stamina is fantastic. The way that he’s singing is incredible.…