A sweeping global review led by researchers at the University of British Columbia has found that mRNA vaccines—now administered billions of times worldwide—are safe and highly effective at preventing infectious diseases like COVID-19, and have potential applications for a range of other diseases, including influenza, RSV, cancer and autoimmune disorders.

Published today in The Lancet , the review draws on laboratory science, clinical trials and real-world effectiveness data to provide one of the most comprehensive assessments of mRNA vaccines to date. It spans the full vaccine lifecycle, from design and manufacturing to real-world performance and monitoring.

By bringing this evidence together in a single resource, the researchers aim to support healthcare providers, policymakers and the public with clear, evidence-based information as new mRNA vaccines and therapies are developed.

“After billions of doses, we now have an extraordinary amount of scientific evidence,” said lead author Dr.…