I moved a table's primary key off random GUIDs a little while back. The reason is the usual one: a clustered index hates random inserts. Every new row wants a spot in the middle of the index instead of the end, pages split, the thing fragments, and your inserts get slower the bigger the table gets. Version 7 GUIDs are the tidy fix. They carry a millisecond timestamp in their leading bytes, so new keys sort roughly in creation order and land near the end where the index wants them.
Before I trusted that in production I wanted to see the ordering with my own eyes. So I did the dumbest thing that would show it: generate a pile of keys and count how many came out in order. The answer made me feel a bit silly.
What v7 actually promises
A v7 GUID isn't random all the way down. The first 48 bits are a Unix millisecond timestamp, then a handful of version and variant bits, then the rest is random. Two keys created in different milliseconds sort by those timestamps.…