Cannabinol (CBN) has become a popular ingredient in sleep supplements, often promoted as a natural, gentle way to relax and get a better night's rest. However, new research from the University of Connecticut suggests that this widely available cannabis compound may have risks that consumers should know about.

Scientists found that repeated exposure to CBN caused mice to develop signs of physical dependence. The findings, published in the November issue of the journal Drug and Alcohol Dependence, raise questions about the safety of using CBN regularly, particularly over long periods.

"CBN is everywhere right now. Gummies, tinctures, capsules, and it's marketed as a safe, herbal sleep supplement," says Steven Kinsey, professor in UConn's Elisabeth DeLuca School of Nursing. "Our findings suggest consumers should be aware repeated use may carry risks."

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CBN is a naturally occurring compound in cannabis, along with THC (tetrahydrocannabinol) and CBD (cannabidiol).…