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Detroit Lions wide receiver Amon-Ra St. Brown (14) runs for a first down against the Green Bay Packers at Ford Field in Detroit, Sunday, Oct. 25, 2026. IMAGN IMAGES via Reuters Connect

It’s a big divisional matchup in Week 8 as the Vikings and Lions meet.

Arguably the league’s best defense heads to Motown to face a beat-up Lions squad that comes in as a 3.5-point favorite, despite Jahmyr Gibbs and Amon-Ra St. Brown popping up on the injury report earlier this week. Neither have an injury designation for this game.

Detroit did received some good injury news recently, though, with Brian Branch returning last week.

Lions vs. Vikings prediction, best bet

Minnesota needs to get its offense into form; its rated No. 2 on defense in DVOA, but a putrid No.…