Key Takeaways

Damon Wayans Sr. jumped at the chance to reunite with David Alan Grier on St. Denis Medical , saying, “They only had to say David wanted you to do this.”

Wayans plays Dr. Highland, a charming but pompous physician filling in while Grier’s Dr. Ron recovers from heart surgery, in the NBC comedy’s Season 3 premiere on Nov. 2.

The former In Living Color partners share few scenes, but Wayans says their decades-long chemistry remains intact and hopes viewers feel their mutual love—and laugh.

Wayans will play Dr. Highland, a charming but pompous physician brought in while Grier's character, Dr. Ron, recovers from heart surgery. Highland immediately becomes the hospital's new favorite, much to the irritation of supervising nurse Alex, played by Allison Tolman.

Of course, this isn't the first time Wayans and Grier have played off each other.…