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Surgeons in imperial China used anaesthetics — in careful doses

Nature·5 months ago
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RESEARCH HIGHLIGHT

29 May 2026

Traces on tweezers and surgical scissors suggest liquid medication was applied to the skin of patients.

Surgical scissors from a Ming-era tomb bore traces of the toxic plant compound aconitine. Credit: Ling, X. et al. / Antiquity (CC BY 4.0)

Anaesthetics are now part of every operating room, but physicians have been trying to reduce pain from surgery for centuries. Chemical traces on fifteenth-century surgical tools suggest that topical anaesthetics were used in China more than 600 years ago 1 .

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