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This organoid can menstruate — and shows how tissue can repair itself

www.nature.com·Steiner, Claudia·6 months ago
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Gynaecological disorders such as endometriosis could be studied using endometrium organoids. Credit: fizkes/Shutterstock

Researchers have developed organoids that can regenerate like the endometrium, the lining of the uterus that sheds and re-forms during the menstrual cycle. The team used the miniature 3D structures to simulate rarely seen repair processes, which could inform future therapeutic strategies for tissue renewal and wound healing. The findings were published in Cell Stem Cell on 28 April 1 .

The endometrium has a unique ability to repair itself after menstrual shedding without scarring, but how it does this is a mystery.…

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