Please don't attack me. I love nearly all of Trek.
Currently on my second bi-annual TNG re-watch, and just heard:
I never learned to speak hypothetical
That was in response to a hypothetical question from Riker in episode "Unification II" (Season 5, Episode 8) which was written by Michael Piller (RIP)
OK, so.. assuming we all love Trek, and the fandom is not going to freaking kill me for asking a question.. are there any one-liners as good as that?