There is a group of defenses that fantasy managers absolutely need to avoid playing in Week 8. With that, here are four of those defenses that are set up to be some of the worst-performing in fantasy this week.

Carolina Panthers

Oct 18, 2026; Philadelphia, Pennsylvania, USA; Carolina Panthers defensive tackle Lee Hunter (92) and linebacker Bobby Okereke (58) during warmups against the Philadelphia Eagles at Lincoln Financial Field. Mandatory Credit: Eric Hartline-Imagn Images | IMAGN IMAGES via Reuters Connect

The Carolina Panthers ' defense has had extreme lows and highs in 2026. Coming off Week 7, where they were tied for being the worst defense in fantasy, they should have another rough outing in Week 8 against the Green Bay Packers.

The Panthers have one of the worst rushing defenses in the NFL, as they are currently allowing the most rushing yards per game in the league: 153.2.…