WASHINGTON — Vice President JD Vance on Wednesday placed the blame for Republicans’ wipeout in the midterm elections squarely on the war with Iran, in a remarkable break from President Donald Trump’s defense of his decision to attack.

In a more than 600-word post on social media, Vance also offered a broader critique of the Trump administration’s agenda and messaging in what appeared to be an effort to separate himself from the president.

“The reason we lost is the war,” Vance wrote. “The president himself said so last night. If you’d like to argue it was worth it, that losing the Senate for the next 6 years was worth it, then do so. Argue it was a worthwhile cost to pay.…