The Colorado Buffaloes showed carry over from their valiant Oct. 17 effort against Utah. But Oklahoma State blew the game open in astonishing fashion, taking the 57-24 rout on Oct. 24 in Stillwater.

Colorado took a 24-23 lead into halftime, only needing to punt the ball away once during the first half. But quarterback Isaac Wilson fumbled the football on the opening play of the third quarter, and things snowballed from there for CU.

The Cowboys scored in six of their last seven offensive possessions from there, whereas Colorado punted four times and watched Wilson throw an interception. Coach Deion Sanders addressed the meltdown in Stillwater with reporters after the game.

Oklahoma State Loss 'Hurts' for Deion Sanders in Opening Statement

The Oklahoma State Cowboys take the field before a college football game between the Oklahoma State Cowboys (OSU) and the Colorado Buffaloes at Boone Pickens Stadium in Stillwater, Okla., Saturday, Oct. 24, 2026. Oklahoma State won 57-24.…