A U.S. cruise ship on a residential world voyage suspended its operations in Cambodia due to fuel costs, forcing hundreds of passengers to abandon their floating homes.

The Odyssey set sail two years ago on a three-year voyage to the seven continents marketed as combining long-term living at sea with global travel.

The Florida-based company said monthly fuel expenses per cabin that historically averaged $1,800 has recently reached an estimated $6,000 to $8,000 in parts of Asia during the war in Iran . Villa Vie Residences said it sought to reduce fuel consumption by slowing the itinerary and spending more time in port, but was unable to offset the surge in fuel costs.

“We have been unable to continue carrying the resulting operating losses,” it said. “Passing the full increase on to residents is not a realistic solution. Our focus now is on supporting residents, crew, and employees" while it tries to restructure.

Sihanoukville Autonomous Port said in a statement last week that the ship docked on Oct.…