A new microscope that can simultaneously measure both forward- and backward-scattered light from a sample could allow researchers to image both micro- and nanoscale objects at the same time. The device could be used to observe structures as small as individual proteins, as well as the environment in which they move, say the researchers at the University of Tokyo who developed it.

“Our technique could help us link cell structures with the motion of tiny particles inside and outside cells,” explains Kohki Horie of the University of Tokyo’s department of physics, who led this research effort. “Because it is label-free, it is gentler on cells and better for long observations.…