Christina Applegate has been battling what she thought was multiple sclerosis since her diagnosis back in 2021. Now, she found out that she was misdiagnosed ; she does not have MS, and whatever has been plaguing her remains a mystery. At first, that sounds like a horrible bit of doctoring by the medical professionals she’s been working with, but MS is a tricky thing to diagnose.

To be clear, it’s not like she’s been magically cured overnight just because she knows she doesn’t have MS. As she explained on her podcast “MeSsy,” she’s “back at square one” with the same debilitating health issues and no clue what’s causing it.

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The fundamental issue with diagnosing MS is that no single, all-encompassing test exists. Doctors must follow a high-stakes neurological process of elimination.…