The Trump Administration has proposed what could be the biggest overhaul in years of how the federal government distributes billions of dollars in grants, requiring senior appointees to conduct “pre-issuance reviews” that critics say pave the way for political interference in what should be independent research funding. The proposal , which was more than 400 pages long and was published in the Federal Register Friday, by the Office of Management and Budget (OMB) calls for the review of awards on several grounds, including whether they “demonstrably advance the President's policy priorities.”  Agencies would also have broad authority to terminate awards if they decide that a grant no longer aligns with government goals or interests, similar to “termination for convenience” provisions in federal contracts.…