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T and B cells recognize splicing-derived neutrophil neoantigens in lupus
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T and B cells recognize splicing-derived neutrophil neoantigens in lupus

#nature#science#cryptic#splicing#events

Proteome diversity is generated through alternative mRNA splicing1. In tumours, mis-spliced transcripts that contain intronic sequences, skipped exons or noncanonical donor/acceptor splice junctions resulting in frameshifts are often translated into…

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