Six sweeteners used in everyday diet products were associated with faster cognitive decline in a large Brazilian study . For calorie-conscious shoppers, the findings offer a reason to check ingredients—and understand the study’s limits.

The six were aspartame, saccharin, acesulfame-K, erythritol, sorbitol and xylitol . Researchers found no association for tagatose, the seventh sweetener examined. This is research first published in 2025, not a new November 2026 trial.

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The Finding Was Strongest Before 60

Researchers followed 12,772 adults, averaging 52 years old, for roughly eight years.…