Data availability

Connectome data were taken from the publicly available datasets referenced throughout 3 , 4 , 5 , 6 . MANC connectome data were analysed from the public release (v.1.2.1). FANC connectome data were analysed from the CAVE materialization (v.1178; timestamp 2025-01-07T10:10:01.373080). Male CNS connectome data were analysed from the public release (v.0.9). BANC connectome data were analysed from the CAVE materialization (v.829; timestamp 2026-02-13T08:10:01.234098). All connectivity and cell information for the exact subnetworks used in this paper are provided at https://github.com/smpuglie/Pugliese_2026 . Simulation output data and Anipose data can be found on Zenodo via https://doi.org/10.5281/zenodo.22260923 .

Code availability

Code to run the connectome simulations and notebooks to reproduce the analyses in each figure are available on GitHub at https://github.com/smpuglie/Pugliese_2026 .

References

Büschges, A. & Ache, J. M.…